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Translational Medicine / 转化医学iPSC-Derived Cell Therapy

Judith Klimkait

PhD

🏢Century Therapeutics🌐USA

Vice President of iPSC Cell Therapy

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👥Biography 个人简介

Judith Klimkait leads iPSC-derived cell therapy development at Century Therapeutics, working on engineering iPSC lines with multiple genetic modifications to create off-the-shelf T cell and NK cell products with enhanced anti-tumor activity and immune evasion capabilities. Her team has developed protocols for efficient differentiation of gene-edited iPSC lines into functional T cells that maintain CAR expression and cytotoxic function. She is advancing multiplexed gene editing approaches to create universal donor iPSC master cell banks.

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🧪Research Fields 研究领域

iPSC-derived allogeneic T cells
Gene-edited iPSC platforms
iPSC differentiation for immunotherapy
Engineered iPSC-T cell manufacturing
Universal donor iPSC lines

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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