Klaus Pantel
克劳斯·潘特尔
MD, PhD
Professor and Chair, Institute of Tumor Biology; Director, Liquid Biopsy Research Program肿瘤生物学研究所主任及主席；液体活检研究项目主任
👥Biography 个人简介
Founding father of circulating tumor cell (CTC) research and a global pioneer of liquid biopsy. Over three decades he elucidated the biology of CTCs and disseminated tumor cells, their role in metastasis, and their clinical utility as prognostic and predictive biomarkers across multiple cancer types.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CTC Biology and Clinical Utility
Established biological characterization of CTCs from breast, prostate, and colorectal cancer, linking CTC counts and molecular profiles to metastatic potential and patient outcomes.
Liquid Biopsy Standardization
Led international efforts to standardize pre-analytical conditions, CTC enumeration methods, and ctDNA assays, enabling multi-center clinical validation studies.
Representative Works 代表性著作
Circulating tumour cells in cancer patients: challenges and perspectives
Trends in Molecular Medicine (2019)
Comprehensive review of CTC biology, detection technologies, clinical applications, and remaining challenges in translating CTCs to routine practice.
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nature Reviews Cancer (2016)
Landmark perspective on ctDNA and CTC clinical translation, outlining the path from research to clinical implementation.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
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