Alexander Khoruts

Alexander Khoruts has been a leader in the clinical development and standardization of fecal microbiota transplantation, establishing protocols for donor screening, preparation, and administration that have been adapted for cancer immunotherapy applications. His work on FMT safety in immunocompromised patients has provided the evidence base for using microbiome restoration in cancer patients undergoing immunotherapy. His donor microbiome banking infrastructure has enabled the randomized clinical trials of FMT in oncology that have demonstrated immunotherapy response modulation.