Ken Kato
加藤健
MD, PhD
Chief, Department of Head and Neck, Esophageal Medical Oncology头颈部及食管内科肿瘤科主任
👥Biography 个人简介
Dr. Ken Kato is Japan's leading expert in esophageal and GEJ cancer, serving as principal investigator of CheckMate 648, which established nivolumab + chemotherapy as first-line standard for esophageal squamous cell carcinoma. He also leads HER2-targeted trials for esophageal adenocarcinoma.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CheckMate 648: Nivolumab in Esophageal SCC
Principal investigator of CheckMate 648, demonstrating that nivolumab + chemotherapy or nivolumab + ipilimumab significantly improved OS vs. chemotherapy alone in first-line esophageal squamous cell carcinoma.
HER2-Targeted Therapy in Esophageal Cancer
Leads clinical research on HER2+ esophageal and GEJ cancer in Japan, including trastuzumab combinations and novel ADC evaluations in this subpopulation.
Representative Works 代表性著作
Nivolumab in combination with chemotherapy or ipilimumab in patients with advanced esophageal squamous cell carcinoma (CheckMate 648)
Journal of Clinical Oncology (2022)
Phase III trial establishing nivolumab-based regimens as first-line standard for advanced esophageal SCC with improved OS in PD-L1-expressing tumors.
Phase II study of trastuzumab plus chemotherapy in HER2-positive esophageal and GEJ adenocarcinoma
Gastric Cancer (2021)
Japanese phase II study demonstrating activity of trastuzumab-based therapy in HER2+ esophageal and GEJ adenocarcinoma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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留下邮箱，当我们发布与 Ken Kato（National Cancer Center Hospital, Tokyo, Japan）相关的新研究或访谈时，我们会通知你。
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