Keith Bible
基思·拜布尔
MD, PhD
Professor of Oncology肿瘤学教授
👥Biography 个人简介
National expert in anaplastic thyroid carcinoma (ATC), one of the most lethal human cancers. Led landmark trials of BRAF V600E-directed therapy with dabrafenib plus trametinib in ATC, achieving remarkable response rates in BRAF-mutant disease and transforming the treatment of this previously untreatable malignancy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Anaplastic Thyroid Carcinoma Treatment
Led pivotal basket trial arms demonstrating striking clinical activity of dabrafenib plus trametinib in BRAF V600E-mutant anaplastic thyroid carcinoma, contributing to the first-ever FDA approval for ATC therapy.
Representative Works 代表性著作
Efficacy of Vemurafenib in Patients With Anaplastic Thyroid Cancer With BRAF V600E Mutation
Journal of Clinical Oncology (2017)
Demonstrated BRAF inhibitor activity in anaplastic thyroid carcinoma, establishing proof-of-concept for molecularly targeted therapy in ATC.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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