Artem Kaznatcheev

Artem Kaznatcheev develops theoretical frameworks combining algorithmic game theory and computational complexity theory with cancer evolution, providing rigorous mathematical foundations for understanding when and why adaptive therapy can control resistance evolution and when it will fail. His research at the University of Oxford has formalized the fitness landscape structure of drug resistance and identified computational hardness results that define fundamental limits on predicting evolutionary outcomes under therapy. His work establishes the theoretical boundaries of evolutionary therapy and informs the design of robust treatment strategies.