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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

Howard Kaufman

MD

🏢Ankyra Therapeutics🌐USA

Chief Medical Officer

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Key Papers
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Key Contributions

👥Biography 个人简介

Howard Kaufman was instrumental in the clinical development of T-VEC (talimogene laherparepvec), the first FDA-approved oncolytic virus immunotherapy for intratumoral injection in melanoma. His clinical trials established that intratumoral oncolytic virus therapy can generate both local and systemic anti-tumor immunity. He continues to advance next-generation intratumoral oncolytic virus combinations with checkpoint inhibitors.

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🧪Research Fields 研究领域

T-VEC oncolytic immunotherapy
Talimogene laherparepvec
Intratumoral oncolytic virus
Melanoma immunotherapy
Oncolytic virus combinations

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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