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Translational Medicine / 转化医学HCC Cabozantinib, Second- and Third-Line HCC

Katie Kelley

MD

🏢University of California San Francisco🌐USA

Professor, Division of Hematology and Oncology

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👥Biography 个人简介

Katie Kelley is a hepatobiliary cancer oncologist who contributed to the CELESTIAL trial establishing cabozantinib as a second- or third-line treatment for advanced HCC. Her research encompasses the tumor microenvironment of HCC, mechanisms of therapeutic resistance, and combinations of TKIs with immune checkpoint inhibitors. She investigates both HCC and biliary tract cancers, addressing FGFR2 and IDH inhibition in intrahepatic cholangiocarcinoma. She is principal investigator of multiple NCI-sponsored hepatobiliary cancer clinical trials at UCSF.

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🧪Research Fields 研究领域

cabozantinib HCC CELESTIAL trial
HCC second-line MET VEGFR cabozantinib
intrahepatic cholangiocarcinoma systemic therapy
advanced HCC multiline treatment
GI malignancy clinical trials UCSF

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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