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Translational Medicine / 转化医学WNT Signaling, Hepatocellular Carcinoma

Kathleen Bhatt

MD

🏢University of Texas MD Anderson Cancer Center🌐USA

Associate Professor of Hepatology

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Key Contributions

👥Biography 个人简介

Kathleen Bhatt specializes in WNT/beta-catenin driven hepatocellular carcinoma, where CTNNB1 activating mutations are among the most common oncogenic events. Her research has characterized how WNT activation rewires hepatic metabolism and drives immune evasion in liver cancer. She has evaluated combinations of WNT inhibitors with immune checkpoint blockade in preclinical models. Her clinical research focuses on stratifying HCC patients by WNT pathway status for targeted treatment.

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🧪Research Fields 研究领域

hepatocellular carcinoma
WNT/beta-catenin
liver cancer
CTNNB1 mutations
targeted therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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