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Translational Medicine / 转化医学CHEK2, ATM Germline Mutations

Katherine Nathanson

MD

🏢University of Pennsylvania Abramson Cancer Center🌐USA

Deputy Director, Abramson Cancer Center

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👥Biography 个人简介

Katherine Nathanson at the Abramson Cancer Center is an expert in moderate-penetrance cancer susceptibility genes, particularly CHEK2 and ATM, which confer intermediate breast and pancreatic cancer risks. Her research has characterized the clinical implications of these variants and contributed to management guideline development for carriers. She has also studied multigene panel testing outcomes and the challenges of variant of uncertain significance interpretation.

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🧪Research Fields 研究领域

CHEK2 breast cancer
ATM germline pancreatic cancer
moderate penetrance breast genes
multigene panel clinical utility
germline cancer risk counseling

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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