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Translational Medicine / 转化医学NK Cell Therapy, iPSC-Derived NK Cells

Katayoun Rezvani

MD, PhD, FRCP

🏢University of Texas MD Anderson Cancer Center🌐USA

Professor; Chief, Cellular Therapy Section

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👥Biography 个人简介

Katayoun Rezvani is a world leader in developing iPSC-derived and cord blood-derived NK cell therapies for hematologic malignancies. She led the landmark clinical study of cord blood-derived CAR-NK cells targeting CD19 in lymphoid malignancies, demonstrating remarkable clinical responses with minimal toxicity compared to CAR-T cells. Her laboratory focuses on scalable manufacturing of NK cell products from iPSCs and cord blood. She has pioneered genetic engineering strategies to enhance NK cell persistence, cytotoxicity, and homing to tumor sites.

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🧪Research Fields 研究领域

iPSC-derived NK cells
cord blood NK CAR engineering
CAR-NK CD19
NK cell manufacturing scale-up
NK cells AML

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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