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Translational Medicine / 转化医学CDK12 Synthetic Lethality
Thomas Karn
PhD
🏢Goethe University Frankfurt🌐Germany
Professor
55
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Key Papers
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Key Contributions
👥Biography 个人简介
Thomas Karn studies CDK12 alterations and genomic instability in breast cancer with implications for immunotherapy and targeted therapy selection. His group analyzes large cohorts to characterize CDK12 mutant tumors and their response to treatment. He has published extensively on biomarkers for DNA damage repair deficient cancers.
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🧪Research Fields 研究领域
breast cancer
CDK12
genomics
biomarkers
DNA damage response
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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