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Translational Medicine / 转化医学Amino Acid Metabolism, p53 and Serine

Karen Vousden

PhD

🏢Francis Crick Institute🌐UK

Senior Group Leader

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Key Contributions

👥Biography 个人简介

Karen Vousden showed how p53 controls serine and glycine biosynthesis to support tumor cell survival under stress. Her work demonstrates that dietary serine restriction can blunt tumor growth in preclinical models. She develops translational nutrient-deprivation strategies in cancer.

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🧪Research Fields 研究领域

p53 metabolism
serine and glycine
one-carbon metabolism
tumor suppressor
dietary intervention

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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