Kai Wucherpfennig
MD, PhD
Chair, Department of Cancer Immunology and Virology
👥Biography 个人简介
Kai Wucherpfennig leads fundamental research into T cell dysfunction and exhaustion in the tumor microenvironment, which underlies resistance to immune checkpoint blockade. His laboratory has elucidated how epigenetic changes drive T cell exhaustion and limit IO efficacy. He has characterized key transcription factors including TOX that maintain the exhausted T cell state. His work informs strategies to reinvigorate exhausted T cells in resistant tumors.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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