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Translational Medicine / 转化医学Senolytic Therapy Clinical Research

Diana Jurk

PhD

🏢Mayo Clinic🌐USA

Associate Professor of Physiology and Biomedical Engineering

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👥Biography 个人简介

Diana Jurk has developed quantitative methods for identifying and measuring senescent cells in vivo using telomere-associated DNA damage foci and other biomarkers, enabling clinical trial endpoints for senolytic therapy evaluation. Her work demonstrating that senescent cell burden in tissues correlates with cancer risk and treatment toxicity has supported clinical development of senolytics. She contributes to biomarker development for senolytic clinical trials in cancer prevention.

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🧪Research Fields 研究领域

Telomere-associated foci
DNA damage and senescence
Neuronal senescence
In vivo senescence quantification
Senescent cell biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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