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Translational Medicine / 转化医学Nasopharyngeal Carcinoma, Southern China NPC Treatment

Jun Ma

MD, PhD

🏢Sun Yat-sen University Cancer Center🌐China

Professor and Vice President, Sun Yat-sen University Cancer Center

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👥Biography 个人简介

Jun Ma is one of China's foremost experts on nasopharyngeal carcinoma, a malignancy with particularly high incidence in southern China and Southeast Asia due to EBV association and genetic susceptibility factors. Her research has contributed to optimizing radiation therapy techniques for NPC including intensity-modulated radiation therapy that significantly reduces late toxicity while maintaining high local control rates, and to establishing induction chemotherapy plus concurrent chemoradiation as the standard approach for locally advanced NPC. She has investigated pembrolizumab and other checkpoint inhibitors in NPC, where EBV-driven viral antigen expression and frequent PD-L1 positivity support immunotherapy rationale, contributing to first approvals of anti-PD-1 therapy in recurrent/metastatic NPC. Her contributions to NPC clinical trials and treatment innovation have advanced care for this endemic cancer affecting populations in southern China, Southeast Asia, and Chinese diaspora communities worldwide.

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🧪Research Fields 研究领域

nasopharyngeal carcinoma radiation therapy
NPC EBV-associated southern China
concurrent chemoradiation NPC
induction chemotherapy NPC
NPC immunotherapy pembrolizumab

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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