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Translational Medicine / 转化医学SCLC Immunotherapy, Thoracic Oncology

Julie Brahmer

MD, MSc

🏢Johns Hopkins Sidney Kimmel Comprehensive Cancer Center🌐USA

Co-Director, Upper Aerodigestive Cancers Program; Professor of Oncology

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👥Biography 个人简介

Julie Brahmer is a pioneer in immunotherapy for thoracic malignancies who conducted early clinical trials demonstrating checkpoint inhibitor activity in SCLC. She contributed to the IMpower133 trial evaluating atezolizumab plus carboplatin-etoposide in extensive-stage SCLC, and has broadly advanced PD-1/PD-L1 inhibitor development across lung cancer histologies. Her early work on anti-PD-1 (nivolumab) safety and efficacy helped launch the field of checkpoint immunotherapy in solid tumors. She is the primary author of the ASCO/NCCN guidelines on immune-related adverse events.

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🧪Research Fields 研究领域

atezolizumab SCLC IMpower133
PD-L1 small cell lung cancer
nivolumab SCLC CheckMate 032
thoracic oncology immunotherapy
lung cancer immune checkpoint inhibitors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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