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Translational Medicine / 转化医学Cancer Biology, Cellular Senescence

Judith Campisi

PhD

🏢Buck Institute for Research on Aging / Lawrence Berkeley National Laboratory🌐USA

Professor Emerita

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Key Contributions

👥Biography 个人简介

Dr. Judith Campisi is a pioneer in cellular senescence research who established the paradoxical roles of senescence in cancer biology: senescence acts as a tumor suppressor mechanism but can also promote cancer through the senescence-associated secretory phenotype (SASP). Her discoveries are foundational to understanding how aging promotes cancer and have catalyzed therapeutic approaches targeting senescent cells and SASP-mediated tumor microenvironment remodeling.

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🧪Research Fields 研究领域

cellular senescence cancer promotion
senescence-associated secretory phenotype SASP
p53 RB senescence tumor suppression
senolytic therapy cancer
aging cancer biology intersection

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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