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Translational Medicine / 转化医学Exon 20 Insertion NSCLC

Joshua Sabari

MD

🏢NYU Langone Perlmutter Cancer Center🌐USA

Assistant Professor of Medicine

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👥Biography 个人简介

Joshua Sabari investigates exon 20 insertion mutations in HER2 and EGFR in NSCLC, defining clinical characteristics and therapeutic strategies for this historically difficult-to-treat population. His work contributed to clinical development of amivantamab, mobocertinib, and novel HER2 exon 20 agents. He advances biomarker-guided trial enrollment for exon 20 alterations.

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🧪Research Fields 研究领域

HER2 exon 20 insertion
EGFR exon 20 insertion
mobocertinib and amivantamab
exon 20 NSCLC biology
clinical development exon 20

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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