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Translational Medicine / 转化医学Waldenstrom's Macroglobulinemia, Treatment

Jorge Castillo

MD

🏢Dana-Farber Cancer Institute / Harvard Medical School🌐USA

Clinical Director, Bing Center for Waldenstrom's Macroglobulinemia

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Key Contributions

👥Biography 个人简介

Jorge Castillo is a leading WM clinician who has led key clinical trials including the ASPEN trial comparing zanubrutinib to ibrutinib in WM, demonstrating superior tolerability with comparable efficacy for zanubrutinib. His research addresses frontline, maintenance, and relapsed WM treatment strategies and the impact of genetic subtypes on outcomes. He contributes to international WM consensus guidelines and has educated the oncology community through numerous review publications.

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🧪Research Fields 研究领域

WM treatment
zanubrutinib WM
ASPEN trial
chemoimmunotherapy WM
BTK inhibitor comparison

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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