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Translational Medicine / 转化医学Ovarian Cancer, Bevacizumab, PARP

Jonathan Ledermann

MD

🏢University College London Cancer Institute🌐UK

Emeritus Professor of Medical Oncology

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Key Contributions

👥Biography 个人简介

Jonathan Ledermann at University College London led the landmark ICON6 bevacizumab trial and the STUDY 19 olaparib maintenance trial that opened the PARP inhibitor era in ovarian cancer. His career of randomized trial leadership has established antiangiogenic and PARP inhibitor maintenance as cornerstones of ovarian cancer management. He was chair of the Gynecological Cancer Intergroup (GCIG) and has coordinated international cooperative group trials. His contributions have directly extended survival for ovarian cancer patients worldwide.

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🧪Research Fields 研究领域

bevacizumab ovarian cancer
ICON trials ovarian
olaparib maintenance
platinum-sensitive ovarian cancer
PARP inhibitor maintenance

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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