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Translational Medicine / 转化医学Ki67 & Proliferation

Stephen Johnston

MA, MD, PhD

🏢Royal Marsden NHS Foundation Trust🌐UK

Professor of Breast Cancer Medicine

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Key Contributions

👥Biography 个人简介

Stephen Johnston led the MonarchE adjuvant trial establishing abemaciclib plus endocrine therapy in high-risk HR-positive breast cancer. He has championed Ki67 as an enrichment biomarker for adjuvant CDK4/6 inhibitor use. His work transformed adjuvant treatment paradigms for proliferative HR-positive disease.

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🧪Research Fields 研究领域

Endocrine therapy
CDK4/6 inhibitors
MonarchE trial
Adjuvant trials
Ki67 response

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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