John Moran
PhD
Professor of Human Genetics and Internal Medicine
👥Biography 个人简介
John Moran is the foremost authority on LINE-1 retrotransposition in human cells, having developed the engineered retrotransposition assay that enabled functional studies of mobile elements. His work demonstrated that somatic LINE-1 insertions occur frequently in cancer genomes, disrupting tumor suppressor genes and driving genomic instability. He has established the mechanistic framework for understanding how retrotransposons contribute to cancer evolution.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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