John Maciejowski
PhD
Assistant Member
👥Biography 个人简介
John Maciejowski has revealed the catastrophic genomic consequences of telomere crisis in cancer initiation. His work demonstrated that dicentric chromosomes formed during telomere crisis are processed by TREX1 nuclease, generating chromothripsis and kataegis that drive rapid cancer genome evolution. These findings established telomere crisis as a key mechanism for the punctuated evolution observed in cancer genomes.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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