John Bhatt
PhD
Professor of Immunology
👥Biography 个人简介
John Bhatt is a structural immunologist specializing in TCR-pMHC interactions and TCR affinity engineering for cancer therapy. His work has elucidated structural mechanisms governing TCR recognition of tumor antigens and cross-reactive normal tissues. He has developed engineering strategies to enhance TCR affinity while maintaining specificity and avoiding off-target recognition. His research provides important safety guidance for the clinical application of affinity-enhanced TCRs in cancer therapy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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