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Translational Medicine / 转化医学mCRPC, Enzalutamide, Abiraterone

Johann de Bono

MBChB, PhD, FRCP

🏢Royal Marsden Hospital / Institute of Cancer Research🌐UK

Professor and Head of Drug Development

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👥Biography 个人简介

Johann de Bono at the Royal Marsden and ICR is one of the most influential figures in prostate cancer drug development, having led trials that established enzalutamide and abiraterone as pillars of mCRPC treatment. He was a co-developer of the RECIST criteria adaptation for prostate cancer and has advanced PARP inhibitors including olaparib in mCRPC through landmark trials. His drug development expertise spans early-phase prostate cancer trials to registration studies. He has received numerous international awards for his transformative contributions to the field.

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🧪Research Fields 研究领域

enzalutamide mCRPC
abiraterone mCRPC
PARP inhibitors mCRPC
mCRPC drug development
prostate cancer clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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