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Translational Medicine / 转化医学Bladder Cancer, Pembrolizumab

Joaquim Bellmunt

MD, PhD

🏢Beth Israel Deaconess Medical Center, Harvard Medical School🌐USA

Director, Bladder Cancer Center

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Key Contributions

👥Biography 个人简介

Joaquim Bellmunt led the pivotal KEYNOTE-045 trial that established pembrolizumab as the first immunotherapy to demonstrate overall survival benefit in platinum-refractory urothelial carcinoma, leading to FDA approval. His research has long focused on prognostic factors and novel systemic therapies for advanced bladder cancer. He contributed to development of the Bellmunt risk score for metastatic urothelial cancer that continues to be used in clinical practice. He is co-director of the Bladder Cancer Center at Beth Israel Deaconess Medical Center.

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🧪Research Fields 研究领域

pembrolizumab urothelial
KEYNOTE-045
second-line bladder cancer
prognostic factors urothelial
bladder cancer clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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