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Translational Medicine / 转化医学Sex Differences, Chromosomes and Cancer

Jennifer Smith

MD, PhD

🏢Johns Hopkins University School of Medicine🌐USA

Associate Professor of Medicine

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👥Biography 个人简介

Dr. Jennifer Smith is a cancer genomics researcher at Johns Hopkins who has investigated the role of sex chromosome alterations in cancer biology. She has contributed to understanding loss of Y chromosome in somatic cells as a cancer risk factor in males and examined how sex-biased gene expression patterns influence tumor immune infiltration. Her work bridges cytogenetics with cancer immunology in a sex-differentiated framework.

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🧪Research Fields 研究领域

sex chromosome cancer biology
Y chromosome loss cancer
CDKN1C sex-biased expression
loss of Y chromosome somatic
sex-biased gene expression tumors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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