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Translational Medicine / 转化医学Fc Receptor Biology, ADCC Engineering
Jeffrey Ravetch
MD, PhD
🏢Rockefeller University🌐USA
Professor of Molecular Genetics and Immunology
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Key Contributions
👥Biography 个人简介
Jeffrey Ravetch defined the biology of Fc gamma receptors and how therapeutic antibody effector function is controlled, driving the development of ADCC-enhanced antibodies. His work underlies afucosylated antibodies such as obinutuzumab and mogamulizumab.
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🧪Research Fields 研究领域
Fc gamma receptor
ADCC engineering
antibody effector function
afucosylation
inhibitory Fc receptor
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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