Jeffrey Engelman
MD, PhD
Chief of Thoracic Oncology and Director of Cancer Program
👥Biography 个人简介
Dr. Jeffrey Engelman is a physician-scientist who made foundational discoveries in MET amplification as a resistance mechanism to EGFR inhibitors in lung cancer. His landmark work demonstrated that MET gene amplification mediates gefitinib resistance through bypass signaling, catalyzing the field of combination EGFR plus MET inhibition. He has transitioned to industry leadership while continuing to shape translational oncology research.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
关注 Jeffrey Engelman 的研究动态
Follow Jeffrey Engelman's research updates
留下邮箱，当我们发布与 Jeffrey Engelman（Massachusetts General Hospital Cancer Center）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment