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Translational Medicine / 转化医学Signatera MRD, Colorectal ctDNA

Jeanne Tie

MBBS, PhD

🏢Peter MacCallum Cancer Centre🌐Australia

Associate Professor, Medical Oncology

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Key Contributions

👥Biography 个人简介

Jeanne Tie at Peter MacCallum Cancer Centre has led landmark trials demonstrating that ctDNA-guided decision-making can improve outcomes in colorectal cancer. She was the principal investigator of the DYNAMIC trials showing that withholding adjuvant chemotherapy based on negative post-operative ctDNA is safe in stage II colon cancer. Her work has advanced ctDNA from research tool to clinical decision-support.

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🧪Research Fields 研究领域

Signatera ctDNA
colorectal cancer MRD
ctDNA-guided adjuvant therapy
DYNAMIC trial ctDNA
stage II-III colon MRD

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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