Jean-Yves Blay
让-伊夫·布莱
MD, PhD
Professor of Medical Oncology; Director, Department of Medical Oncology医学肿瘤学教授；内科肿瘤科主任
👥Biography 个人简介
Jean-Yves Blay, MD PhD is Professor at Centre Léon Bérard and one of Europe's preeminent sarcoma oncologists. He founded and leads the European Reference Network for rare solid tumors (ERN-EURACAN) and the EuroSarc consortium. His research encompasses GIST molecular pathology, leiomyosarcoma biology, and pan-sarcoma genomic profiling through the MULTISARC and AcSé programs.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
European Sarcoma Network Leadership
Founded EuroSarc and co-created ERN-EURACAN, the EU reference network for rare solid tumors, enabling pan-European clinical trials, molecular tumor boards, and harmonized sarcoma care across 30+ countries.
GIST and STS Genomics
Led landmark genomic profiling studies in GIST and leiomyosarcoma through the MULTISARC program, identifying actionable mutations and co-developing French national sarcoma treatment guidelines (RREPS/NetSarc).
Representative Works 代表性著作
Genomic Grade Index Predicts Postoperative Clinical Outcome in Patients with Soft Tissue Sarcoma
Annals of Oncology (2019)
Validated a genomic grade index for STS risk stratification, enabling more precise prognostication and adjuvant therapy decisions in clinical practice.
Pazopanib for Metastatic Soft-Tissue Sarcoma (PALETTE): A Randomised, Double-Blind, Placebo-Controlled Phase 3 Trial
Lancet (2012)
Key investigator in PALETTE establishing pazopanib as a standard second-line option for non-adipocytic STS, an approval that reshaped European treatment algorithms.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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