Jean-Pierre Issa
M.D.
Director and CEO
👥Biography 个人简介
Jean-Pierre Issa is a leader in cancer epigenetics who has advanced understanding of how DNA methylation changes contribute to cancer and aging. His clinical research has established low-dose decitabine and azacitidine regimens for myelodysplastic syndromes, now standard treatments.
Jean-Pierre Issa是癌症表观遗传学的领导者，推进了对DNA甲基化变化如何导致癌症和衰老的理解。他的临床研究确立了用于骨髓增生异常综合征的低剂量地西他滨和阿扎胞苷方案，现已成为标准治疗。
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Epigenetic Therapy
Established low-dose hypomethylating agent regimens for MDS.
Aging Epigenetics
Characterized epigenetic drift with aging and its role in cancer.
Representative Works 代表性著作
DNA methylation in aging and cancer
Current Opinion in Oncology (2000)
Linking aging epigenetics to cancer risk.
📄Data Sources 数据来源
Last updated: 2026-03-05 | All information from publicly available academic sources
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留下邮箱，当我们发布与 Jean-Pierre Issa（Coriell Institute for Medical Research）相关的新研究或访谈时，我们会通知你。
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