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Translational Medicine / 转化医学Radiation Biology, FLASH Radiation Therapy Ultra-High Dose Rate

Jean Bourhis

MD, PhD

🏢CHUV Lausanne University Hospital🌐Switzerland

Professor and Chairman, Radiation Oncology

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Key Contributions

👥Biography 个人简介

Jean Bourhis led the first-ever clinical application of FLASH radiation therapy in a human patient with an exceptionally high dose rate electron beam, demonstrating feasibility and remarkable sparing of normal tissue. His work has catalyzed the field of FLASH radiobiology and has contributed to understanding the potential oxygen depletion mechanism underlying differential normal tissue protection at ultra-high dose rates. He continues to lead clinical FLASH trials.

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🧪Research Fields 研究领域

FLASH radiation therapy UHDR
ultra-high dose rate radiobiology
FLASH normal tissue protection
proton FLASH clinical trial
FLASH oxygen depletion mechanism

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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