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Translational Medicine / 转化医学Adjuvant Pembrolizumab Stage IIB/C Melanoma

Jason Luke

MD

🏢UPMC Hillman Cancer Center🌐USA

Associate Professor and Director of Cancer Immunotherapeutics Center

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👥Biography 个人简介

Jason Luke led KEYNOTE-716 establishing adjuvant pembrolizumab for high-risk stage IIB and IIC resected melanoma, expanding adjuvant IO indications to earlier stages. His work demonstrated significant recurrence-free survival benefit in patients historically observed without systemic therapy. He continues to refine risk-adapted adjuvant selection.

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🧪Research Fields 研究领域

KEYNOTE-716
stage IIB/IIC adjuvant pembrolizumab
early-stage melanoma adjuvant IO
distant metastasis-free survival
adjuvant IO expansion

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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