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Translational Medicine / 转化医学Progesterone Receptor and Translation, Breast Cancer

Janet Rowley

MD

🏢University of Chicago (Historical)🌐USA

Blum-Riese Distinguished Service Professor (Historical)

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👥Biography 个人简介

Janet Rowley (deceased 2013) discovered balanced chromosomal translocations in leukemia, including t(9;22) in CML and t(8;21), founding the field of cancer cytogenetics and recurrent gene fusions. Her framework influenced broader thinking about transcriptional dysregulation including in hormone-driven cancers.

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🧪Research Fields 研究领域

chromosomal translocations
cytogenetics pioneer
CML Philadelphia chromosome
gene fusion oncology
historical pioneer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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