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Translational Medicine / 转化医学NOTCH Signaling, Colorectal Cancer, Intestinal Biology

Janet Bhatt

MD, PhD

🏢Vanderbilt-Ingram Cancer Center🌐USA

Associate Professor of GI Oncology

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👥Biography 个人简介

Janet Bhatt studies NOTCH signaling in colorectal cancer and its crosstalk with the WNT pathway in intestinal stem cell biology. Her research has defined how NOTCH activity regulates intestinal crypt cell fate decisions and how dysregulation contributes to colorectal tumorigenesis. She has characterized the interplay between NOTCH and WNT signaling in controlling cancer stem cell pools within colorectal tumors. Her preclinical work has evaluated dual inhibition of NOTCH and WNT pathways as a therapeutic strategy in colorectal cancer.

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🧪Research Fields 研究领域

NOTCH signaling
colorectal cancer
intestinal crypt biology
WNT-NOTCH crosstalk
cancer stem cells

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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