James W. Welsh
詹姆斯·韦尔什
MD
Professor, Department of Radiation Oncology; Director, Radiation and Immunity Laboratory放射肿瘤学系教授；放射与免疫实验室主任
👥Biography 个人简介
James Welsh directs the Radiation and Immunity Laboratory at MD Anderson Cancer Center and is a pioneering investigator in combining radiation with immune checkpoint blockade, leading landmark trials of concurrent ipilimumab and radiation in lung cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
First Radiation + Ipilimumab Trial
Led one of the first clinical trials combining radiation with ipilimumab (anti-CTLA-4) producing documented abscopal responses in lung cancer.
SBRT + Checkpoint Inhibitors
Established that hypofractionated SBRT combined with checkpoint inhibitors can convert systemic immune tolerance to anti-tumor immunity.
Optimal Radiation-Immunotherapy Sequencing
Developed preclinical models defining optimal sequencing and timing of radiation with immunotherapy for maximum synergistic effects.
Representative Works 代表性著作
Abscopal effect associated with systemic immune activation in patients with advanced NSCLC
Cancer Immunology Research (2016)
First prospective documentation of abscopal responses with radiation + ipilimumab, transforming the field.
Phase II trial of ipilimumab plus radiation in metastatic non-small cell lung cancer
Journal of Thoracic Oncology (2017)
Established safety and preliminary efficacy signals for radiation + CTLA-4 blockade combination.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Brian Marples
University of Rochester Medical Center
Silvia C. Formenti
Weill Cornell Medicine / NewYork-Presbyterian Hospital
Paul M. Harari
University of Wisconsin School of Medicine and Public Health
Jeff Forman
Wayne State University / Karmanos Cancer Institute
关注 詹姆斯·韦尔什 的研究动态
Follow James W. Welsh's research updates
留下邮箱，当我们发布与 James W. Welsh（The University of Texas MD Anderson Cancer Center）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment