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Translational Medicine / 转化医学T-Cell Engager, Prostate Cancer

James Gulley

MD, PhD

🏢National Cancer Institute🌐USA

Director, Center for Immuno-Oncology

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Key Contributions

👥Biography 个人简介

Dr. James Gulley is a prominent immunotherapy researcher at the NCI whose laboratory has investigated PSMA-targeting bispecific T-cell engagers including pasotuxizumab in prostate cancer. He has contributed to understanding immune resistance mechanisms in prostate cancer and rational combination strategies to enhance BiTE activity in the immunosuppressive prostate tumor microenvironment. His group has published landmark work on cancer vaccines and T-cell based therapies.

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🧪Research Fields 研究领域

PSMA BiTE pasotuxizumab
PSMA bispecific prostate cancer
cancer immunotherapy solid tumors NCI
prostate tumor immune evasion
BiTE prostate clinical development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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