James Bhatt

James Bhatt is an expert in hereditary colorectal cancer risk assessment and genetic testing for colorectal cancer predisposition syndromes. His research has characterized pathogenic variants in mismatch repair and other colorectal cancer predisposition genes across diverse populations. He has developed and validated polygenic risk scores for CRC that complement single-gene testing for identifying high-risk individuals. His work on variant of uncertain significance classification has improved the clinical interpretation of germline testing in colorectal cancer families.