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Translational Medicine / 转化医学Cancer Biology, Proto-Oncogenes

J. Michael Bishop

MD

🏢University of California San Francisco🌐USA

Chancellor Emeritus

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Key Contributions

👥Biography 个人简介

J. Michael Bishop shared the 1989 Nobel Prize with Harold Varmus for the discovery that retroviral oncogenes are derived from normal cellular proto-oncogenes — genes that regulate growth and can be converted to cancer-causing oncogenes by mutation or aberrant expression. This landmark discovery established the genetic basis of cancer and has guided cancer drug development for over 40 years.

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🧪Research Fields 研究领域

proto-oncogenes
viral oncogenes
src kinase
cancer genetics
Nobel Prize 1989

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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