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Translational Medicine / 转化医学Milestone Clinical Trials

Jean-Pierre Issa

MD

🏢Coriell Institute for Medical Research🌐USA

Director Coriell Institute for Medical Research

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Key Contributions

👥Biography 个人简介

Jean-Pierre Issa is a pioneer of epigenetic therapy and led foundational trials of hypomethylating agents in myeloid malignancies. His work established azacitidine and decitabine as standards for myelodysplastic syndromes. He has published influential studies on DNA methylation in cancer. He is among the leading epigenetics investigators in oncology.

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🧪Research Fields 研究领域

epigenetic therapy
DNA methylation
myelodysplastic syndromes
clinical trials
hypomethylating agents

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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