Irving Weissman
MD
Virginia and D.K. Ludwig Professor of Clinical Investigation
👥Biography 个人简介
Prof. Irving Weissman is the discoverer of cancer stem cells and a pioneer in innate immune checkpoint biology including CD47. He identified that cancer cells overexpress CD47 to send a 'do not eat me' signal to macrophages through SIRPalpha, providing the basis for anti-CD47 therapies in development. His research on combining CD47 blockade with phagocytosis-promoting antibodies has opened a new innate immunity checkpoint therapeutic category.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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