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Translational Medicine / 转化医学NF2/Merlin, LATS1/2, Hippo Pathway

Ingo Bhatt

PhD

🏢University of Heidelberg🌐Germany

Tumor Biologist

22
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Key Papers
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Key Contributions

👥Biography 个人简介

Ingo Bhatt studies the NF2/Merlin tumor suppressor and the Hippo signaling pathway in cancer. NF2 loss causes neurofibromatosis type 2 and mesothelioma, and activates the YAP/TAZ transcriptional co-activators through Hippo pathway deregulation. The Hippo-YAP/TAZ axis is now recognized as a major driver of multiple cancer types and a potential therapeutic target, with YAP/TAZ inhibitors in early clinical development.

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🧪Research Fields 研究领域

NF2 merlin tumor suppressor
Hippo pathway cancer
LATS1 LATS2 cancer
YAP TAZ cancer
mesothelioma NF2

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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