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Translational Medicine / 转化医学Prostate Cancer Prevention, Finasteride

Ian Thompson

MD

🏢UT Health San Antonio🌐USA

Professor of Urology

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Key Contributions

👥Biography 个人简介

Ian Thompson at UT Health San Antonio led the Prostate Cancer Prevention Trial (PCPT) — the first trial to demonstrate that a pharmacological agent (finasteride) reduces prostate cancer incidence. The PCPT showed a 25% reduction in prostate cancer prevalence with finasteride but also increased detection of high-grade tumors, creating a nuanced result that has shaped debate about prostate cancer chemoprevention for two decades.

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🧪Research Fields 研究领域

prostate cancer prevention
finasteride PCPT
dutasteride REDUCE trial
5-alpha reductase inhibitors
prostate cancer chemoprevention

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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