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Translational Medicine / 转化医学Tumor Microenvironment, pH Therapy

Ian Tannock

MD, PhD

🏢Princess Margaret Cancer Centre / University of Toronto🌐Canada

Emeritus Professor of Medical Oncology

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Key Contributions

👥Biography 个人简介

Ian Tannock performed pioneering work on tumor pH as a determinant of chemotherapy response and the weak-base trapping phenomenon affecting drug distribution. His mentorship and writing shaped a generation of clinical oncologists. He remains an active critic of cancer trial interpretation.

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🧪Research Fields 研究领域

tumor pH therapy
weak base drug trapping
hypoxia
chemotherapy resistance
clinical trial methods

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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