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Translational Medicine / 转化医学Pancreatic Cancer KRAS

Christine Iacobuzio-Donahue

MD, PhD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Chair, Department of Pathology

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Key Contributions

👥Biography 个人简介

Christine Iacobuzio-Donahue is a pioneering pathologist whose autopsy-based studies transformed understanding of pancreatic cancer metastasis and molecular evolution. Her work revealed the clonal architecture and KRAS-dependent progression of pancreatic ductal adenocarcinoma. She has established foundational concepts in how pancreatic cancers evolve and spread.

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🧪Research Fields 研究领域

Pancreatic cancer pathology
Metastasis biology
Autophagy
KRAS mutations
Molecular evolution

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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