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Translational Medicine / 转化医学Prostate Cancer, Circulating Tumor Cells

Howard Scher

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

D. Wayne Calloway Chair in Urologic Oncology

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Key Contributions

👥Biography 个人简介

Howard Scher at Memorial Sloan Kettering co-led the AFFIRM trial establishing enzalutamide in post-docetaxel mCRPC and has made fundamental contributions to understanding androgen receptor biology, AR-V7 splice variant as a resistance biomarker, and circulating tumor cell analysis for response monitoring in prostate cancer. His work connecting AR biology to therapeutic resistance drives ongoing treatment innovation.

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🧪Research Fields 研究领域

prostate cancer
AFFIRM trial
enzalutamide
circulating tumor cells
AR splice variants

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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