Hiroshi Maeda
PhD MD
Professor Emeritus
👥Biography 个人简介
Hiroshi Maeda discovered the EPR (enhanced permeability and retention) effect — the tendency of macromolecules and nanoparticles to preferentially accumulate in tumors due to leaky tumor vasculature and poor lymphatic drainage. This foundational concept has been the theoretical basis for passive tumor targeting by nanomedicines for decades, and his polymer-drug conjugate SMANCS was the first approved macromolecular anticancer drug in Japan.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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