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Translational Medicine / 转化医学Sortase Antibody Conjugation

Hidde Ploegh

PhD

🏢Boston Children's Hospital🌐USA

Senior Investigator

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Key Papers
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Key Contributions

👥Biography 个人简介

Hidde Ploegh pioneered sortase-mediated site-specific protein conjugation enabling homogeneous antibody-drug conjugates and nanobody imaging agents. His chemistry has shaped next-generation ADC development for oncology.

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🧪Research Fields 研究领域

sortase-mediated conjugation
site-specific antibody labeling
antibody-drug conjugate
nanobody imaging
ADC engineering

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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